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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMF1
All Species:
33.33
Human Site:
S494
Identified Species:
45.83
UniProt:
P82094
Number Species:
16
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P82094
NP_009045.2
1093
122842
S494
F
R
V
K
E
E
S
S
S
I
S
S
L
K
D
Chimpanzee
Pan troglodytes
XP_526227
1093
122795
S494
F
R
V
K
E
E
S
S
S
I
S
S
L
K
D
Rhesus Macaque
Macaca mulatta
XP_001088711
1092
122828
S493
F
R
V
K
E
E
S
S
S
I
S
S
L
K
D
Dog
Lupus familis
XP_533766
1089
122761
S491
F
R
V
K
E
E
S
S
S
I
S
S
L
K
D
Cat
Felis silvestris
Mouse
Mus musculus
B9EKI3
1091
121796
S492
F
R
V
K
E
E
S
S
S
I
S
S
L
K
D
Rat
Rattus norvegicus
NP_446123
1093
121882
S494
F
R
V
K
E
E
S
S
S
I
S
S
L
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510334
1106
124384
S501
F
R
V
K
E
E
S
S
S
I
S
S
L
K
D
Chicken
Gallus gallus
O42184
1433
161009
A620
W
K
S
K
L
E
S
A
I
A
S
H
Q
Q
A
Frog
Xenopus laevis
Q5PQ23
649
75475
L150
L
G
K
C
E
E
Q
L
A
A
S
K
R
L
L
Zebra Danio
Brachydanio rerio
NP_001003522
1136
126986
S529
I
S
L
K
E
E
S
S
S
V
Q
S
L
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572360
933
103794
I433
I
L
Q
Q
S
T
I
I
K
K
L
R
A
K
E
Honey Bee
Apis mellifera
XP_394037
1326
150590
E561
N
S
T
I
E
P
A
E
A
E
H
S
I
E
I
Nematode Worm
Caenorhab. elegans
P02566
1966
225108
E1135
S
E
L
E
E
E
L
E
N
E
R
Q
S
R
S
Sea Urchin
Strong. purpuratus
XP_785821
1176
131318
Y574
E
K
R
K
N
E
T
Y
D
L
H
N
L
T
D
Poplar Tree
Populus trichocarpa
XP_002303293
975
109171
I476
Q
A
A
Q
E
S
T
I
R
K
L
R
A
Q
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WVL7
956
108335
K457
A
E
G
E
E
L
S
K
K
Q
A
A
Q
E
A
Baker's Yeast
Sacchar. cerevisiae
P47166
707
81153
E208
D
L
E
Y
E
V
S
E
L
N
D
S
S
A
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.5
93.1
N.A.
87.2
86.7
N.A.
81.2
21.7
22.6
59.7
N.A.
26.1
23.9
21
37.7
Protein Similarity:
100
99.4
99.1
96.1
N.A.
92.5
92
N.A.
88.3
39.9
37.3
74.6
N.A.
45.8
44.9
36.6
56.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
26.6
20
66.6
N.A.
6.6
13.3
13.3
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
53.3
26.6
80
N.A.
20
40
40
53.3
Percent
Protein Identity:
25.8
N.A.
N.A.
27.1
21.1
N.A.
Protein Similarity:
47.2
N.A.
N.A.
45.4
39.4
N.A.
P-Site Identity:
6.6
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
40
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
6
6
0
0
0
6
6
12
12
6
6
12
6
12
% A
% Cys:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
0
0
0
0
0
0
0
6
0
6
0
0
0
53
% D
% Glu:
6
12
6
12
83
71
0
18
0
12
0
0
0
12
6
% E
% Phe:
42
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
6
6
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
6
0
0
0
% H
% Ile:
12
0
0
6
0
0
6
12
6
42
0
0
6
0
12
% I
% Lys:
0
12
6
59
0
0
0
6
12
12
0
6
0
53
0
% K
% Leu:
6
12
12
0
6
6
6
6
6
6
12
0
53
6
6
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
6
0
0
0
6
0
0
0
6
6
0
6
0
0
0
% N
% Pro:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% P
% Gln:
6
0
6
12
0
0
6
0
0
6
6
6
12
12
6
% Q
% Arg:
0
42
6
0
0
0
0
0
6
0
6
12
6
6
0
% R
% Ser:
6
12
6
0
6
6
65
48
48
0
53
59
12
0
6
% S
% Thr:
0
0
6
0
0
6
12
0
0
0
0
0
0
6
0
% T
% Val:
0
0
42
0
0
6
0
0
0
6
0
0
0
0
0
% V
% Trp:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
6
0
0
0
6
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _